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B030148 - GENERAL PHARMACOLOGY
Main information
Teaching Language
Course Content
Learning Objectives
Type of Assessment
Course program
Academic Year 2021-22
Coorte 2019 - 5-years Single Cycle Degree in PHARMACY
Course year
Third year - First Semester
Belonging Department
Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA)
Course Type
Single education field course
Scientific Area
BIO/14 - PHARMACOLOGY
Credits
6
Teaching Hours
48
Teaching Term
27/09/2021 ⇒ 15/01/2022
Attendance required
No
Type of Evaluation
Final Grade
Course Content
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Course program
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Lectureship
Teaching Language
Italian
Course Content
Pre-clinical and Clinical trial of drugs. Pharmacokinetic: absorption, distribution, metabolism and elimination. Pharmacodynamic: actions of drugs mediated by receptors; actions of drugs on enzymatic systems; actions of drugs on carriers, on ion channels, on transporter and pumps. Tolerance. Physical dependence. Withdrawal syndrome. Idiosyncratic and Allergic reactions. Drug-drug interactions and Drug-food interactions
Learning Objectives
Provide knowledge on the principles of general pharmacology to illustrate and clarify the basic knowledge essential for proper medication managment. Furthermore, the fundamental knowledge regarding the main interactions between drugs and food-drugs, important for drug safety management
Type of Assessment
Oral examination. A question will concern Pharmacokinetic and the whole exam will last about 30 min. Every year there are 5 exam sections plus 2 during the possible periods of ‘didactical silence' in November and April.
Course program
Pre-clinical and Clinical trial of drugs: Phases of clinical trial.
Pharmacokinetic: transfer of drugs across biological membranes; administration routs of drugs; distribution of drugs in body; metabolism of drugs; excretion of drugs. Pharmaco-dynamic: actions of drugs not mediated by receptors; actions of drugs on enzymatic systems; actions of drugs mediated by receptors; actions of drugs on carriers; actions of drugs on ion channels. Desensitization of receptors. Tolerance. Physical dependence. Withdrawal syndrome. Tachyphylaxis. Idiosyncratic and Allergic reactions. Drug-drug interactions and Drug-food interactions
Pharmacokinetic: transfer of drugs across biological membranes; administration routs of drugs; distribution of drugs in body; metabolism of drugs; excretion of drugs. Pharmaco-dynamic: actions of drugs not mediated by receptors; actions of drugs on enzymatic systems; actions of drugs mediated by receptors; actions of drugs on carriers; actions of drugs on ion channels. Desensitization of receptors. Tolerance. Physical dependence. Withdrawal syndrome. Tachyphylaxis. Idiosyncratic and Allergic reactions. Drug-drug interactions and Drug-food interactions