General concepts on carbon and functional groups in organic chemistry. Conjugated derivatives and resonance. Acids and bases. Chemical reactivity basics. Alkanes. Isomerism and stereochemistry. Alkenes and alkynes. Alkyl halides. Alcohols and thiols. Ethers, sulphides and epoxides. Alkyl amines. Benzene and aromatic compounds. Aldehydes and ketones. Carboxylic acids and derivatives. Introduction to bioorganic chemistry. Lipids, carbohydrates, peptides and nucleic acids.
Textbooks:
J. Gorzynski Smith “Fondamenti di Chimica Organica” Ed. Mc Graw Hill
B. Botta "Chimica Organica" Ed. Edi. Ermes
Learning Objectives
Knowledge acquired: Acquisition of base concepts relative to the properties and reactivity of organic molecules
Competence acquired (at the end of the course): Knowledge of the most important reactions of organic molecules and the relative mechanisms
Skills acquired (at the end of the course): Interpretation of the behavior of organic reactions and subsequently of biochemical mechanisms
Prerequisites
Courses recommended: General and inorganic chemistry
Teaching Methods
Total hours of the course (including the time spent in attending lectures,
seminars, private study, examinations, etc...): 225
Hours reserved to private study and other individual formative activities: 153
Contact hours for: Lectures/practice (hours): 72
Type of Assessment
Exam modality: Oral examination
Oral examination details: oral examination will be carried out with the aid of writing of molecules and reaction mechanisms.
Evaluation parameters: learning verification, critical reasoning skills, expertise in the use of specialized vocabulary.
Course program
Atomic structure and atomic orbitals. The chemical bond. Carbon atom and hybrid orbitals. Writing molecules. Conjugated derivatives and resonance. Aromaticity. Acids and bases. Energy diagrams and chemical reactivity basics. Alkanes and cicloalkanes. Isomerism. Nomenclature. Conformations. Stereoisomerism, chirality, enantiomers, disteroisomers. Optical activity. Alkenes and Alkynes. Electrophilic additions. Alkyl halides. Nucleophilic substitution and beta-elimination. Structure, nomenclature, properties and reactivity: alcohols and thiols; ethers, sulphides and epoxides; alkyl amines. Benzene and aromatic compounds. Aromatic electrophilic substitution. Carbonylic compounds and nucleophilic addition. Reactions on alfa carbon. Carboxylic compounds and derivatives. Acylic nucleophilic substitutions. Introduction to bioorganic chemistry. Structure, properties and hints of reactivity: lipids, carbohydrates (mono-, di-, polisaccharides), aminoacids (peptides and proteins), nucleic acids.