Bacci e coll. Cellula e tessuti edi-ermes.
e coll. Di Prinio e coll. Istologia Umana Idelson-Gnocchi.
Paroli G, Puliti E, Bacci S. L'atlante di istologia per scienze biologiche. Master Books
Puliti E, Paroli G, Bacci S. Preparati microscopici dei fondamenti di embriologia per scienze biologiche. Master Books
Learning Objectives - Last names M-Z
At the end of the course the student will be able to describe the organization of the cell and the different tissues in relation with the different functions and the early events of morphogenesis.
Prerequisites - Last names M-Z
Fundamental knowledge of biology, chemistry, and biochemistry
The exam consists of a preliminary admission test and an oral exam.
Course program - Last names M-Z
The living substance: general, structural, functional and molecular characteristics.
Techniques and principles of light and electron microscopes.
General characteristics of the eukaryotic cell.
The plasma membrane: molecular organization, structure and functions.
Ribosomes, an outline of protein synthesis.
Membranous organelles of secretory pathways: rough endoplasmic reticulum, Golgi apparatus; exocytosis.
Endocytotic pathway: lysosomes, processes and mechanisms of endocytosis
Smooth endoplasmic reticulum.
Peroxisomes: structure and functions.
Mitochondria: morphology, functions and origin, an outline of cell respiration.
Cytoskeleton: microtubules, microfilaments, intemediate filaments: cellular movements, centrioles.
Nucleus: nuclear envelope, nucleolus, nucleoplasm, chromatin (condensed and extended). Chromosomes, Cellular cycle. Mitosis and Meiosis.
Gametes, ovulation, gametogenesis, menstrual cycle, fertilization. Morphological events from first to fourth week of development. Derivatives of ectoderm, entoderm, mesoderm. Cellular populations, stem cells. Apoptosis, necrosis.
Surface epithelial tissue: histogenesis, classification and main characteristics. Differentiation of cellular surface: microvilli, cilia, intercellular and cell-matrix junctions.
Transformed epithelia (including hard keratin appendages).
Connective tissue proper: cells, intercellular substance, basement membrane, classification.
Supporting connettive tissues:
cartilage tissue, bone tissue, ossification processes.
Blood and haematopoiesis.
Muscle tissues: classification and structure.
Nervous tissue: neurons, synapses, glial cells, nervous
Laboratory activity
Observation and identification at light microscopy of specimens of tissues studied during the course
Analysis of digital images of cells and tissues. Introduction to digital images and methods for morphometric analysis and image segmentation of cell and tissue images. Analysis of digital histology slides.